Adolescent health has been identified by the Royal Government of Cambodia as a priority. Aligning with this; the World ¶¹ÄÌÊÓƵAPP and GFF through ADLAB; will support the development of adolescent health and well-being case studies in Cambodia. This work; which builds on health priorities of the Royal Government of Cambodia and the objectives of ADLAB and the GFF Global Youth Platform; aims to build the capacity of young Cambodian researchers and will also provide more understanding of the health and well-being needs of adolescents and other young people. The work aims to identify evidence gaps relevant to policy and program decision-makers; generate evidence in response to those gaps through the case studies; and translate findings into products and recommendations that are interpretable and usable by policy and program decision-makers. In addition to building capacity of individual researchers and strengthening the evidence ecosystem in Cambodia; it aims to engage different local stakeholders working on adolescent health in Cambodia; and more broadly provide insights to inform the World ¶¹ÄÌÊÓƵAPP and GFF¡¯s adolescent health agenda.